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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC2
All Species:
10
Human Site:
S346
Identified Species:
20
UniProt:
Q9UIJ5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UIJ5
NP_057437.1
367
42022
S346
S
Q
S
W
T
E
S
S
I
N
P
G
K
C
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098564
322
36847
T302
Q
S
W
T
E
S
S
T
N
P
G
K
C
K
A
Dog
Lupus familis
XP_532825
322
36792
T302
Q
S
W
T
E
S
S
T
N
P
G
K
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P59267
366
41963
S345
S
Q
T
W
T
E
S
S
A
N
P
G
K
G
K
Rat
Rattus norvegicus
Q9JKR5
366
42067
S345
S
Q
T
W
T
E
N
S
S
N
S
G
R
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508925
327
37361
T307
Q
S
W
A
E
S
S
T
N
S
D
M
D
T
V
Chicken
Gallus gallus
XP_420689
376
42780
G355
T
H
S
W
S
D
I
G
A
K
A
E
K
G
K
Frog
Xenopus laevis
Q5FWL7
338
39422
L318
E
N
Q
W
E
D
D
L
T
D
E
E
S
Q
A
Zebra Danio
Brachydanio rerio
NP_001013510
361
41903
G341
L
N
N
G
Q
T
D
G
S
E
D
R
D
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
V378
S
E
K
E
I
K
S
V
D
D
E
I
T
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYP5
307
34670
L287
P
G
Y
T
E
E
D
L
R
R
M
P
E
L
Q
Baker's Yeast
Sacchar. cerevisiae
P42836
336
39165
R316
L
E
D
Q
L
L
R
R
V
T
P
R
P
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86
85.5
N.A.
95
95.3
N.A.
77.3
82.4
50.6
74.3
N.A.
N.A.
N.A.
32.7
N.A.
Protein Similarity:
100
N.A.
86.6
86.3
N.A.
96.7
97.5
N.A.
80.9
89.3
67.8
84.4
N.A.
N.A.
N.A.
50.6
N.A.
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
80
66.6
N.A.
6.6
26.6
6.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
86.6
86.6
N.A.
20
46.6
20
13.3
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
41.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
17
0
9
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% C
% Asp:
0
0
9
0
0
17
25
0
9
17
17
0
17
0
0
% D
% Glu:
9
17
0
9
42
34
0
0
0
9
17
17
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
17
0
0
17
25
9
17
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
9
0
0
9
0
0
0
9
0
17
25
25
34
% K
% Leu:
17
0
0
0
9
9
0
17
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
17
9
0
0
0
9
0
25
25
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
17
25
9
9
0
0
% P
% Gln:
25
25
9
9
9
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
9
9
9
9
0
17
9
0
17
% R
% Ser:
34
25
17
0
9
25
50
25
17
9
9
0
9
9
0
% S
% Thr:
9
0
17
25
25
9
0
25
9
9
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
9
% V
% Trp:
0
0
25
42
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _